Mathematical Modeling

Watanabe MA, Fenton FH, Evans SJ, Hastings HM, Karma A. A mechanism for discordant alternans. J Cardiovasc Electrophysiol 2001; 12:196-206

WatanabeMA, Koller ML. A mathematical analysis of the dynamics of cardiac memory and accommodation. Theory and experiment. Am J Physiol 2002; 282:H1534-H1547.

Osaka M, Kumagai H, Sakata K, Onami T, Chon KH, Watanabe MA, Saruta T. Low-order chaos in sympathetic nerve activity and scaling of heartbeat intervals. Phys Rev E Stat Nonlin Soft Matter Phys 2003; 67:041915

Shiferaw Y, Watanabe MA, Garfinkel A, Weiss JN, Karma A. Model of intracellular calcium cycling in ventricular myocytes. Biophys J 2003; 85(6):3666-86.

Osaka M, Watanabe MA. A modified Chua circuit simulates 1/f-like fluctuation of heartbeat intervals. International Journal of Bifurcation and Chaos 2004; 14:3449-3457

Watanabe MA. Editorial Commentary: Standard restitution curves during action potential duration alternans. Heart Rhythm 2006; 3(6):720-1.


Heart Rate Turbulence, noninvasive risk prediction

Marine JE, Watanabe MA, Smith TW, Monahan KE. Effect of atropine on heart rate turbulence. Am J Cardiol 2002; 89:767-9

Watanabe MA, Marine JE, Sheldon RS, Josephson ME. Effects of ventricular premature stimulus coupling interval on blood pressure and heart rate turbulence. Circulation 2002; 106:325-330

Barthel P, Bauer A, Schneider R, Watanabe MA, Ulm K, Schmidt G. Reduction of prognostic power of ventricular late potentials in post-myocardial infarction patients in the reperfusion era. European Heart Journal 2005 ;26(8):755-61.

Watanabe MA, Guzik P. Letter regarding Prevalent Low-Frequency Oscillation of Heart Rate: Novel Predictor of Mortality After Myocardial Infarction, by Wichterle et al. Circulation 2005;111:e180-181

Watanabe MA. Editorial Commentary: Role of hypotension in heart rate turbulence. Heart Rhythm 2005; 2(8):828-9

Bauer A, Watanabe MA, Barthel P, Schneider R, Ulm K, and Schmidt G. QRS duration and late mortality in unselected post-infarction patients of the revascularization era. Eur Heart J. 2006; 27(4):427-33

Bauer A, Malik M, Barthel P, Schneider R, Watanabe MA, Camm J, Schömig A, Schmidt G. Turbulence dynamics: An independent predictor of late mortality after acute myocardial infarction. Int J Cardiol. 2006; 107(1):42-7.

Watanabe MA. Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications. J Cardiovasc Electrophysiol. 2006; 17(7):735-40.

Watanabe MA, Alford MG, Schneider R, Bauer A, Barthel P, Stein PK, Schmidt G. Demonstration of circadian rhythm in heart rate turbulence using novel application of correlator functions. Heart Rhythm 2007; 4:292-300


In SUBMISSION

Watanabe MA, Bhalodia R, Lundequam EJ, Domitrovich PP, Stein PK, Freedland K, Duntley SP, Carney RM. Increased vnetircular premature contraction frequency during rapid eye movement sleep in obstructive sleep apnea. Submitted to European Heart Journal.

Watanabe MA, Kucenas S, Bowman T, Knuepfer MM. Angiotensin II and CRF receptors in the central nucleus of the amygdala mediate vascular responses to cocaine in conscious rats. Submitted to Journal of Pharmacological and Experimental Therapeutics.


Review articles

Watanabe MA. Heart rate turbulence: a review. Indian Pacing and Electrophysiology Journal 2003;3:10-22 (www.ipej.org/0301/watanabe.htm)

Watanabe MA and Schmidt G. Heart rate turbulence: a 5 year review. Heart Rhythm 2004;1:732-738

Watanabe MA and Watanabe Y. Heart rate turbulence. Its electrophysiology and clinical significance. Heart 2004; 36:799-808 (in Japanese)

Francis J, Watanabe MA and Schmidt G. Heart rate turbulence: a new predictor for risk of sudden cardiac death. Ann Noninvasive Electrocardiol 2005;10:102-9


Book Chapter

Schneider R, Barthel P, Watanabe MA. Chapter 20. Heart rate turbulence on Holter. In: Malik M, Camm JN editors. Dynamic Electrocardiography. Blackwell Publishing 2004




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